DepartmentCellular and Integrative Physiology
Elizabeth Gould, Ph.D.
Jun Hee Kim, Ph.D.
Dr. Gould earned her PhD in Neuroscience from the University of Colorado, Denver in August 2017, where she studied the role of oligodendrocytes, the myelin producing cell in the central nervous system, in neural circuit function. As a postdoctoral researcher in Dr. Jun Hee Kim’s lab, Dr. Gould continues to study oligodendrocytes and how they modulate neural function through bi-directional communication. Neuronal activity shapes oligodendrocyte development and myelination; however, the cellular and molecular mechanisms through which this occurs are currently unknown. The first aim of Dr. Gould’s work is to understand how oligodendrocyte excitability modulates their response to neuronal activity. The second aim of Dr. Gould’s work focuses on how oligodendrocytes influence neuronal activity by modulating synapse function. Bi-directional signaling between oligodendrocytes is essential for neural circuit development and function. To study the cellular and molecular mechanisms of neuron-oligodendrocyte communication, Dr. Gould utilizes a combination of genetic models, electrophysiology, Ca2+-imaging, immunohistochemistry, and behavioral testing.