Seminar Series – Jennifer W. Hill, Ph.D.
Event Date & TimeMarch 25, 2019 at 12:00 PM
Jennifer W. Hill, Ph.D.
Dept. of Physiology and Pharmacology
University of Toledo
“Dissociating PVH pathways controlling metabolism and sexual behavior”
Videoconference to AT&T 1.120
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About the Speaker(s)
Melanocortins, produced by POMC neurons in the arcuate nucleus of the hypothalamus, have profound effects on food intake, energy homeostasis, and blood glucose regulation. However, the potential of melanocortin receptor agonists to treat obesity has been hampered by numerous side effects. In particular, the effects of melanocortins on sexual function and behavior is understudied. Our recent data shows melanocortin receptors in the paraventricular nucleus of the hypothalamus (PVH) are critical to these effects. By elucidating downstream melanocortin circuitry, we hope to provide unique targets for pharmacotherapies treating obesity or sexual dysfunction.