Selected Publications

Bhaskaran, S., Butler, J.A., Becerra, S., Fassio, V., Girotti, M., and Rea, S.L. (2011). Breaking Caenorhabditis elegans the easy way using the Balch homogenizer: An old tool for a new application. Analytical Biochemistry.

Butler, J.A., Ventura, N., Johnson, T.E., and Rea, S.L. (2010). Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolism. FASEB J 24, 4977-4988.

Rea, S.L., Graham, B.H., Nakamaru-Ogiso, E., Kar, A., and Falk, M.J. (2010). Bacteria, yeast, worms, and flies: Exploiting simple model organisms to investigate human mitochondrial diseases. Developmental Disabilities Research Reviews 16, 200-218.

     Wu D, Rea SL, Cypser JR, Johnson TE. Mortality shifts in Caenorhabditis elegans: remembrance of conditions past. Aging Cell. 2009 Dec;8(6):666-75.

Ventura N, Rea SL, Testi R. Long-lived C. elegans mitochondrial mutants as a model for human mitochondrial-associated diseases. Exp Gerontol. 2006 Oct;41(10):974-91.

Rea SL, Wu D, Cypser JR, Vaupel JW, Johnson TE. A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. Nature Genet. Aug;37(8):894-8.

Wu D, Rea SL, Yashin AI, Johnson TE. Visualizing hidden heterogeneity in isogenic populations of C. elegans. Experimental Gerontology Mar;41(3):261-70.

Ventura N, Rea SL, Henderson ST, Condo I, Testi R, Johnson T.E. C. elegans as a model for Friedreich Ataxia. FASEB J. May;20(7):1029-30.

Henderson, ST, Rea, SL, Johnson, TE. Dissecting the Processes of Aging Using the Nematode Caenorhabditis elegans. Handbook of the Biology of Aging, (6th Edition). 2005. (Eds. Edward J. Masoro, Steven N. Austad) (book chapter).

Ventura N, Rea S, Henderson ST, Condo I, Johnson TE, Testi R. Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans. Aging Cell. 2005 Apr;4(2):109-12.

Rea, S.L. Metabolism in the Caenorhabditis elegans Mit mutants. Exp Gerontol. 2005 Nov;40(11):841-9.

Widberg CH, Bryant NJ, Girotti M, Rea S, James DE. Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation. J Biol Chem. 2003 Sep 12;278(37):35093-101.

Morrow IC, Rea S, Martin S, Prior IA, Prohaska R, Hancock JF, James DE, Parton RG. Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation. J Biol Chem. 2002 Dec 13;277(50):48834-41.

Dermine JF, Duclos S, Garin J, St-Louis F, Rea S, Parton RG, Desjardins M. Flotillin-1-enriched lipid raft domains accumulate on maturing phagosomes. J Biol Chem. 2001 May 25;276(21):18507-12.

Hekimi S, Bénard C, Branicky R, Burgess J, Hihi AK, Rea S. Why only time will tell. Mech Ageing Dev. 2001 May 31;122(7):571-94.

Rea S, Martin LB, McIntosh S, Macaulay SL, Ramsdale T, Baldini G, James DE. Syndet, an adipocyte target SNARE involved in the insulin-induced translocation of GLUT4 to the cell surface. J Biol Chem. 1998 Jul 24;273(30):18784-92.

Zeng Q, Subramaniam VN, Wong SH, Tang BL, Parton RG, Rea S, James DE, Hong W. A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane. Mol Biol Cell. 1998 Sep;9(9):2423-37.

Macaulay SL, Rea S, Gough KH, Ward CW, James DE. Botulinum E toxin light chain does not cleave SNAP-23 and only partially impairs insulin stimulation of GLUT4 translocation in 3T3-L1 cells. Biochem Biophys Res Commun. 1997 Aug 18;237(2):388-93.

Rea S, James DE. Moving GLUT4: the biogenesis and trafficking of GLUT4 storage vesicles. Diabetes. 1997 Nov;46(11):1667-77. Review.

Ventura N, Rea SL, Schiavi A, Torgovnick A, Testi R, Johnson TE. p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress. Aging Cell. 2009 Apr 22.