Selected Publications

Herlihy JT, Semenov I,  Brenner R, Assessment of airway hyperresponsiveness in murine tracheal rings. Methods Mol Biol, 2013, 1032: 257-269.

Evseev A, Semenov I, Archer CR, Medina JL, Dube PH, Shapiro MS, Brenner R, Functional effects of KCNQ K+ channels in airway smooth muscle, Frontiers Physiol, 2013, in press.

Semenov, I, Herlihy J T, Brenner R. In vitro measurements of tracheal constriction using mice. J Vis Exp, 2012, doi:3703

Wilcox KS and Brenner R, Potassium Channelopathies of Epilepsy, Jaspers Basic Mechanisms of Epilepsy, Chapter 59, 4th edition, 2012, New York: Oxford University Press.

Neuroscience Related Publications:

Shruti S., Urban-Ciecko J, Fitzpatrick JA, Brenner R, Bruchez MP, and Barth AL, The brain-specific Beta4 subunit downregulates BK channel cell surface expression., PLoS One, 2012, 7(3):e33429

Semenov I, Wang B, Herlihy JT, Brenner R: BK Channel beta1 Subunits Regulate Airway Contraction Secondary to M2 Muscarinic Acetylcholine Receptor Mediated Depolarization. J Physiol. 2011, 589(7):1803-1817.

Jaffe DB, Wang B, Brenner R: How Type I and Type II BK channels differentially shape action potentials, Neurosci., 2011, 192:205-218.

Petrik D, Wang B, Brenner R: The modulatory beta4 subunit prevents phosphorylation-dependent activation of BK channels in dentate gyrus granule neurons, Euro. J. Neurosci., 2011, 34:695-704.

Petrik D, Chen QH, Brenner R: BK Potassium Channel Mutations Affecting Neuronal Function and Epilepsy, In: Scott. C. Baraban, Editor. Neuromethods, Animal Models of Epilepsy: Methods and Innovations, May 2009.

Wang B, Rothberg BS, Brenner R: Mechanism of increased BK channel activation from a channel mutation that causes epilepsy, J Gen Physiol., 2009, 133(3):283-94.

Wang B, Chen QH, Brenner R. Proepileptic effects of BK channel gene mutations In: Philip A. Schwartzkroin, Editor. Encyclopedia of Basic Epilepsy Research. Elsevier Press; 2009.

Seibold MA, Wang B, Eng C, Kumar G, Beckman KB, Sen S, Choudhry S, Meade K, Lenoir M, Watson HG, Thyne S, Williams LK, Kumar R, Weiss KB, Grammer LC, Avila PC, Schleimer RP, Burchard EG, and Brenner R: An African-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity, 2008 Hum Mol Genet, 17(17):2681-90.

Grimm PR, Foutz RM, Brenner R and Sansom SC: Identification and localization of BK-beta subunits in the distal nephron of the mouse kidney. Am J Physiol Renal Physiol, 2007 293(1):350-359.

Petrik D and Brenner R: Regulation of STREX BK channels by the Accessory Beta4 Subunit. 2007 Neuroscience, Nov 23; 149(4):789-803

Semenov I, Wang B, Herlihy JT, Brenner R: BK Channel ß Subunit Regulation of Calcium Handling and Constriction in Tracheal Smooth Muscle. 2006, 291 (14):802-810.

Wang B, Brenner R: An S6 mutation in BK channels reveals beta1 subunit effects on intrinsic and voltage-dependent gating. J Gen Physiol 2006 Dec;128(6):731-744.

Pakhomov AG, Semenov I, Brenner R, Toney GM: Hydraulically coupled microejection technique for precise local solution delivery in tissues. J. Neurosci. Meth. , 2006, 155(2):231-40.

Wang B, Rothberg BS, Brenner R: Mechanisms of b4 subunit modulation of BK channels. J Gen Physiol., 2006, 127(4):449-65

Dodd RL, Saito A, Brenner R, Patterson AJ, Chan P, Aldrich RW. The Role of Calcium-Activated Potassium Channels in the Mouse Model of Chronic Cerebral Vasospasm In: Macdonald RL. Cerebral vasospasm : advances in research and treatment. New York: Thieme; 2005. p. 32 - 35.

Brenner R, Chen Q, Vilaythong A, Toney G, Noebels JL, Aldrich, RW: BK channel beta4  subunit reduces dentate gyrus excitability and protects against temporal lobe seizures, Nat Neurosci, 2005, 8(12):1752-9.

Patterson AJ, Henrie-Olson J, and Brenner R. Vasoregulation at the molecular level: a role for the beta1 subunit of the calcium-activated potassium (BK) channel. Trends Cardiovasc Med, 2002, 12, 78-82.