Molecular, Cellular and Integrative Physiology (MCIP) Ph.D. Track
Graduate Program Handbook
Click here to download the Graduate Program Handbook.
The following courses are required for the MCIP Ph.D. track:
Fall Semester I
INTD 5008 IMGP Laboratory Rotations
2 Credit Hours
This course provides and opportunity for students to participate in research activities in the laboratories of faculty members in different tracks to learn laboratory skills and to gain an introduction to the research fields of faculty members. Required Fall and Spring of first year.
INTD 5000 Fundamentals of Biomedical Sciences
8 Credit Hours
This is a core course covering the fundamentals of biochemistry, molecular biology, cell biology, microbiology, immunology, and organismal & systems biology. The course is designed for first year graduate students matriculating into the integrated, multidisciplinary graduate program.
Spring Semester I
INTD 5008 IMGP Laboratory Rotations
2 Credit Hours
This course provides and opportunity for students to participate in research activities in the laboratories of faculty members in different tracks to learn laboratory skills and to gain an introduction to the research fields of faculty members. Required Fall and Spring of first year.
PHYL 5045 Mammalian Physiology
4 Credit Hours
This course begins with fundamental processes that govern membrane transport, membrane potential, and excitation-contraction coupling. The course then proceeds to coverage of organ system function including cardiovascular, respiratory, renal, gastrointestinal and endocrine/metabolic physiology. Lecture material is enhanced by supplemental discussion of research literature encompassing molecular biology, integrative function, and pathophysiological implications. Students may take the full course but are only required to take three out of the four modules (PHYL
5041, 5042, 5043, and 5044).
Mammalian Physiology Modules:
PHYL 5041 - Excitable Membranes
1 Credit Hour
This course addresses fundamental mechanisms of cell excitability in neurons and other excitable tissues. The format is a combination of lectures, readings/discussion, laboratory demonstrations, and simulation software (where available). Examples of the latter include software to simulate the resting membrane potential, action potentials, and synaptic events. This module will emphasize contemporary issues in the scientific literature as well as translational science where dysfunction in channels and synapses underlie common disorders such as Alzheimer's Disease, Myasthenia Gravis, Cystic Fibrosis, Long QT Syndrome, and Epilepsy to name just a few.
PHYL 5042 - Cardiovascular Physiology
1 Credit Hour
The course explores the physiological mechanisms by which the cardiovascular system carries out its principle functions. Mechanisms that produce and regulate cardiac pumping, organ blood flow, capillary fluid and solute exchange, and arterial blood pressure are examined. The nature and importance of various local, neural, and hormonal mechanisms are emphasized. Integrated control of cardiovascular function in situations requiring cardiovascular adjustments (e.g., exercise, blood pressure alterations) are also covered.
PHYL 5043 – Respiratory & Renal Physiology
1 Credit Hour
This course covers the physiology of respiratory and renal function in the human body. Our focus is on basic mechanisms of function, role in body homeostasis, as well as dysfunction of both systems associated with pulmonary and renal disease. Two sessions are set aside for discussion around significant advances in each field. One or more recently published articles will serve as the focus for each of these discussion sessions.
PHYL 5044 - Endocrine/Metabolism & Gastrointestinal Physiology
1 Credit Hour
The course serves to expose students to the current state of knowledge in the field of endocrinology and metabolism, including reproductive physiology, and the related topics of the physiology of the digestive tract. Three sessions are assigned to advanced topics. In these three sessions students will engage in a discussion format centered around one recent important publication. The lecturer will lead the discussion with the aim of showing how the topics the students have been exposed to integrate one with another, providing the context for present day discoveries.
Summer Semester I
PHYL 6097 – Research
6 credit hours
Fall Semester II
PATH 5021 Introduction to Biostatistics
3 Credit Hours
Emphasis is upon application of statistical methods to biological problems. Topics include descriptive statistics, probability, hypothesis testing and estimation.
OR
CSBL 5095 Experimental Design & Data Analysis
2 Credit Hours
The purpose of this course is to provide an introduction to experimental design and statistical analysis. The emphasis of the course will be on the selection and application of proper tests of statistical significance. Practical experience will be provided in the use of both parametric and nonparametric methods of statistical evaluation. Among the topics to be covered are: data reduction, types of distributions, hypothesis testing, scales of measurement, chi square analysis, the special case of the comparison of two groups, analysis of variance, a posteriori multiple range tests, tests of the assumptions of parametric analyses, advanced forms of the analysis of variance, linear regression and correlation analysis.
PHYL 6091 Selected Topics in Physiology*
2 Credit Hours
PHYL 6090 Seminar
1 Credit Hour
The course is comprised of research presentations by Physiology graduate students. This course is required of all students each semester.
PHYL 6097 Research
Credit Hours TBD
Spring Semester II
INTD 6002 Ethics in Research
0.5 Credit Hours
This course will deal with topics relevant to ethics in scientific research. The course will be taught on a "case study" basis, dealing with real and hypothetical situations relevant to the conduct of scientific research. Topics discussed will include, but will not be limited to: data management, peer review, recognizing scientific misconduct, authorship and The University of Texas regulations relevant to human and animal research.
PHYL 6091 Selected Topics in Physiology*
2 Credit Hours
PHYL 6090 Seminar
1 Credit Hour
The course is comprised of research presentations by Physiology graduate students. This course is required of all students each semester.
PHYL 6097 Research
Credit Hours TBD
Qualifying Examination (QE) proposal due prior to May 1st
Remaining Semesters
Summer
PHYL 6097 – Research
6 Credit Hours
Fall/Spring
PHYL 6090 – Seminar
1 Credit Hour
The course is comprised of research presentations by Physiology graduate students. This course is required of all students each semester. Required each semester through graduation.
PHYL 7099 – Dissertation
8 Credit Hours
OTHER COURSES- Selected topics in physiology or coursework as desired by mentor.
All students are required to submit a dissertation research proposal the Spring semester following passing the qualifying exam. Dissertation research proposal is to be presented during the PHYL 6090 Spring Student Seminar course.
*Students are required to attend Monday Physiology Department Seminars/Special Seminars followed by student roundtable luncheon.
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*SELECTED TOPICS IN PHYSIOLOGY (PHYL 6091)
2 Credit Hours
At least two courses selected from among the offerings in:
PHYL 6091-01: Cardiovascular
PHYL 6091-03: Cell Biology in Neural Science
PHYL 6091-04: Endocrine and Metabolism
PHYL 6091-05: Molecular Physiology
PHYL 6091-07: Ion Channels in Disease
Courses that may be substituted for one of these selections:
INTD 5040: Fundamentals of Neuroscience I: Molecular, Cellular & Developmental Neuroscience (3 Credit Hours)
INTD 5043: Fundamentals of Neuroscience II: Systems Neuroscience (3 Credit Hours)
INTD 7002: Neurobiology of Learning and Memory
CSBL 6058: Neurobiology of Aging (2 Credit Hours)
*Not all selected topics are offered each semester, please discuss with Track Leader/Academic Coordinator for more details. Substituted courses will require approval from Track Leader/COGS.
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