The Texas Biomedical Research Institute

The Texas Biomedical Research Institute (TBRI; http://www.txbiomed.org) represents a nearby private, nonprofit scientific institution with over 400 employees and 480,000 square feet of space that includes laboratories, offices, an animal hospital, a library, and specially designed animal facilities. This infrastructure supports numerous NIH-sponsored biomedical studies in infectious disease, cancer research, heart disease and neonatal disorders. In 2011, TBRI formed a partnership with the San Antonio Vaccine Development Center (SAVE), to coordinate vaccine development activities across San Antonio. The TBRI is home to the Southwest National Primate Research Center (SNPR) which sustains the world’s largest captive baboon population, the largest chimpanzee census of any NRPC, has the capacity for nonhuman primate studies in biosafety level 4 facilities, and a veterinary technical staff experienced in the management and use of nonhuman primates. Institute scientists have also developed a fully pedigreed colony of 2,200 laboratory opossums, which are increasingly recognized as an important animal model to carry out research in a broad range of areas including human development, physiology, and disease susceptibility. The TBRI also supports statistical genetic/genomic analyses for several genetic epidemiological studies focused on cardiovascular disease including the Genetics of Atherosclerosis in Mexican Americans (the San Antonio Family Heart Study), Diet and Genotype in Primate Atherosclerosis, Oman Family Study, and Strong Heart Family Study. Most investigators (scientists) at the TBRI are cross-appointed to various academic departments within the UTHSCSA. Thus, there is a rich scientific interchange via these partnership programs that benefit and contribute to the overall scientific excellence available to our trainees in San Antonio. This affiliation contributes to the on-going participation of TBRI scientists and postdoctoral fellows in UTHSCSA-supported trainee programs including the San Antonio Postdoctoral Research Forum (SAPRF) described above.