The San Antonio Military Medical Center (SAMMC) is the largest military medical complex in the nation with Department of Defense (DoD) support provided for state-of-the art trauma research facilities. SAMMC plays a critical role in patient care (primarily wounded service members), graduate medical education and research. With 425-inpatient beds, SAAMC is the only Level 1 trauma center of the DoD on the US mainland and treats more than 2,000 “priority one” patients with life-threatening injuries annually. In addition, 40 beds are dedicated to the US Army Institute of Surgical Research (USAISR; http://www.usaisr.amedd.army.mil/), which operates the only Department of Defense Burn Center (the Army Burn Center) as well as the Combat Casualty Care Research and the Joint Trauma System. The USAISR/SAMMC includes a robust research enterprise that includes unique clinical investigations, diverse animal models to study tissue responses to injury and disease, and diverse fellowship and training opportunities (for postdoctoral, undergraduate, and high school trainees). Importantly, these research programs include a long history of clinical and research collaborations with the UTHSCSA. As outlined above, USAISR postdoctoral trainees (and their mentors) are interested and active participants in UTHSCSA postdoctoral career development programs including the SAPRF. Prior trainees (and faculty) of this NRSA have transitioned into research positions at the USAISR.